Name _______________________________ Date ________ Section _____

 

1.  Define / describe each of the following words / terms as they apply to microbiology.

 

      a.         infection 

     

 

      b.         disease

 

 

      c.         resident flora (a.k.a. normal microflora)

 

 

      d.         List at least 4 groups included among the resident flora.

                  1.

 

                  2.

 

                  3

 

                  4.

 

      e.         Pathogen

 

 

      f.          true pathogen

     

 

      g.         opportunistic pathogen

     

 

      h.         broad spectrum

 

 

3.  A.  List four “portals of entry” exploited by infectious microorganisms

 

      (1)  __________________________________________________

                 

      (2)  __________________________________________________

 

      (3)  __________________________________________________

 

      (4)  __________________________________________________

3. B.  3.  List four “portals of exit” exploited by infectious microorganisms

 

      (1)  __________________________________________________

                 

      (2)  __________________________________________________

 

      (3)  __________________________________________________

 

      (4)  __________________________________________________

 

 

4.  Briefly describe/list four (or so) key stages in the process of infection

 

      a.

 

      b.                    

 

      c.

 

      d.

     

5.  Infectious dose and virulence

 

      a. What is an “infectious dose”? 

 

      b. What is meant by the “virulence” of an organism?

 

       c. How does the “virulence” of a disease organism influence the "infectious dose"?                                

.

 

6.  List 5 to 7 mechanisms by which infectious organisms employ to adhere to (stick to) a surface (cells, fomites, etc)

      a.        

 

      b.

 

      c.

 

      d.

 

      e.

 

      f.

 

      g.

 

7.  Briefly describe three virulence factors possessed by bacterial pathogens.

     

      a.        

 

      b.

 

      c.

 

 

8.  Define / describe each of the following words / terms as they apply to microbial infections.

     

      a. Localized infection

 

      b. systemic infection

 

      c. Focal infection

 

      d. Mixed infection

 

      e. Primary infection

 

      f. Secondary infections

 

9.  Distinguish between a “sign” and a “symptom” with regard to infectious            disease.

      __________________________________________________________

 

      __________________________________________________________

 

      ___________________________________________________________

 

 

10.  What is meant by the term “sequela” (pl. sequelae) of a disease?

 

 

 

 

11.  What is epidemiology?  What is a “reportable (notifiable) disease”?

 

 

 

12.  Distinguish between the morbidity rate and the mortality rate of a disease.

 

 

 

13.  Define / describe each of the following words / terms as they apply to epidemiology

     

      a. Prevalence

 

      b. Incidence

 

      c. Endemic

     

      d. Sporadic

 

      e. epidemic

     

      f. Pandemic

 

 

            14.  What is a “reservoir” of infection?  How can it play a role in controlling a disease?

 

           

 

            15.  A.  Give an example of the spread of a disease by direct contact.

 

                       

                   B.  Give an example of the spread of a disease by indirect contact.          

 

 

            16.  What is a nosocomial infection? 

           

 

                    What are the three most common forms of nosocomial infections?

                        a.

 

                        b.

 

                        c.

 

 

            17.  Relate the development of Koch’s Postulates to the main theme of this chapter’s topics.